Periodic Classification of Local Anaesthetics (Procaine Analogues)

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Periodic Classification of Local Anaesthetics (Procaine Analogues)

Algorithms for classification are proposed based on criteria (information entropy and its production). The feasibility of replacing a given anaesthetic by similar ones in the composition of a complex drug is studied. Some local anaesthetics currently in use are classified using characteristic chemical properties of different portions of their molecules. Many classification algorithms are based ...

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Using Chemical Structural Indicators for Periodic Classification of Local Anaesthetics

Algorithms for classification and taxonomy based on criteria as information entropy and its production are proposed. Some local anaesthetics, currently in use, are classified using five characteristic chemical properties of different portions of their molecules. Many classification algorithms are based on information entropy. When applying the procedures to sets of moderate size, an excessive n...

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Neurotoxicity Comparison of Two Types of Local Anaesthetics: Amide-Bupivacaine versus Ester-Procaine

Local anaesthetics (LAs) may lead to neurological complications, but the underlying mechanism is still unclear. Many neurotoxicity research studies have examined different LAs, but none have comprehensively explored the distinct mechanisms of neurotoxicity caused by amide- (bupivacaine) and ester- (procaine) type LAs. Here, based on a CCK8 assay, LDH assay, Rhod-2-AM and JC-1 staining, 2',7'-di...

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Information entropy and the classification of local anaesthetics

Algorithms for classification and taxonomy based on criteria such as information entropy and its production are proposed. As an example, the feasibility of replacing a given anaesthetic by similar ones in the composition of a complex drug is studied. Some local anaesthetics currently in use are classified using characteristic chemical properties of different portions of their molecules. Many cl...

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Periodic Indices of Serum Amyloid A Following Rumenotomy with Assorted Local Anaesthetics and Sutures in the Sahel Goat

Objective- This study aims at validating the use of serum amyloid A (SAA) as biomarkers of surgical stress using Quantitative ELISA in the Sahel goats. The experiment evaluated SAA profiles of Sahel goats post Diazepam-Lidocaine (DLC) and Diazepam-Bupivacaine (DBC) local anaesthesia. Expressions of SAA in the Sahel goat post rumen skin clamp fixation techniques of rumenotomy wi...

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ژورنال

عنوان ژورنال: International Journal of Molecular Sciences

سال: 2006

ISSN: 1422-0067

DOI: 10.3390/i8010012